Meet-U 2017 was implemented at Université Pierre et Marie Curie (UPMC) and Univ Paris-Sud - Univ Paris-Saclay, in France. In total, 28 students grouped in 6 teams participated. The jury was composed of 4 researchers coming from Paris area.
Subject: The topic of the course was in structural bioinformatics, more specifically protein-protein docking. The students had to conceive, design, develop, test and validate a computational program to predict the three-dimensional structure of a protein complex, given the structures of the two monomeric partners.
Question: Given two proteins A and B, whose 3D structures are known, what is the 3D conformation of the A-B complex?
Expected product: An executable implementing: (i) a docking algorithm (sampling of the conformational space) and (ii) a scoring function to evaluate the candidate conformations. The program had to be handled with a documentation.
Referent teachers: Elodie Laine for UPMC, Anne Lopes for UPSUD-UPSaclay.
Jury members : M. Delarue (Institut Pasteur, Paris), R. Guérois (CEA, Saclay), Y. Ponty (Ecole Polytechnique, Palaiseau) and S. Sacquin-Mora (IBPC, Paris).
Challenge-Colloquium day: It took place on the 20th of January 2017, in Orsay. About one hundred people were present. More details here.